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Diseases

Genetic and Rare Diseases Information Center (GARD)

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Familial hemiplegic migraine type 1


Other Names for this Disease

  • FHM1
  • Hemiplegic migraine, familial type 1
  • MHP1
  • Migraine, familial hemiplegic 1, with progressive cerebellar ataxia
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Treatment

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How might hemiplegic migraine be treated?

Treatment of hemiplegic migraine varies depending on severity and which symptoms are most problematic for the patient. In general, treatments aim to manage symptoms. Drugs that are effective in the prevention of common migraines may be used in hemiplegic migraine.[1] Prophylactic management is applied to patients with frequent, long lasting, or severe attacks. Examples of migraine drugs that have been tried with variable success in people with hemiplegic migraine, include oral verapamil, acetazolamide, lamotrigine.[1]

There are a few articles describing the use of nasal administration of ketamine, intravenous verapamil, and triptans for treatment of aura in people with hemiplegic migraine. Use of triptans in hemiplegic migraine is controversial and may be contraindicated in people with severe attacks.[1]

For further information on these and other treatments, we recommend that you speak with your healthcare provider.
Last updated: 8/26/2013

References
  1. Jen JC. Familial Hemiplegic Migraine. GeneReviews. September 2009; http://www.ncbi.nlm.nih.gov/books/NBK1388/#fhm.Clinical_Description.


Management Guidelines

  • GeneReviews provides current, expert-authored, peer-reviewed, full-text articles describing the application of genetic testing to the diagnosis, management, and genetic counseling of patients with specific inherited conditions. Click on the link to view the article on this topic.
  • Orphanet Emergency Guidelines is an article which is expert-authored and peer-reviewed that is intended to guide health care professionals in emergency situations involving this condition.  

Clinical Trials & Research for this Disease

  • Orphanet lists clinical trials, research studies, and patient registries enrolling people with this condition. Click on Orphanet to view the list.
Other Names for this Disease
  • FHM1
  • Hemiplegic migraine, familial type 1
  • MHP1
  • Migraine, familial hemiplegic 1, with progressive cerebellar ataxia
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.