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Hypomelanosis of Ito
Other Names for this Disease
- Incontinentia pigmenti achromians
- Incontinentia pigmenti type 1 (formerly)
- IPA
- ITO
- Ito hypomelanosis
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Overview
Hypomelanosis of Ito, also called incontinentia pigmenti achromians, is a rare birth defect that causes streaked, whirled, or mottled patches of light-colored skin. These skin changes often develop within the first two years of life. Other symptoms may include varying degrees of learning disability, seizures, increased body hair, scoliosis, and strabismus. The underlying cause of the condition is currently unknown. Girls tend to be affected more commonly than boys.[1][2]
References
- Incontinentia pigmenti achromians. MedlinePlus. http://www.nlm.nih.gov/medlineplus/ency/article/001461.htm. Accessed February 24, 2012.
- Vergine G. Ito hypomelanosis. Orphanet. http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=EN&Expert=435. Accessed February 24, 2012.
Your Questions Answered
by the Genetic and Rare Diseases Information Center1 question(s) from the public on Hypomelanosis of Ito have been answered. See questions and answers. You can also submit a new question.
On this page
General Information
- DermNet NZ is an online resource about skin diseases developed by the New Zealand Dermatological Society Incorporated. DermNet NZ provides information about this condition. Click on the link to view the information.
- MedlinePlus, a Web site designed by the National Library of Medicine to help you research your health questions, provides more information about this topic. Click on the link to view this information.
- Medscape Reference provides information on this topic. Click on the link to view this information. You may need to register to view the medical textbook, but registration is free.
- The National Organization for Rare Disorders (NORD) is a federation of more than 130 nonprofit voluntary health organizations serving people with rare disorders. Click on the link to view information on this topic.
- Orphanet is a European reference portal for information on rare diseases and orphan drugs. Access to this database is free of charge. Click on the link to read information on this topic.
- PubMed is a searchable database of medical literature and lists journal articles that discuss Hypomelanosis of Ito. Click on the link to view a sample search on this topic.
- The The Online Mendelian Inheritance in Man (OMIM) database contains genetics resources that discuss Hypomelanosis of Ito. Click on the link to go to OMIM and review these resources.
Selected Full-Text Journal Articles
- Shobha N, Taly AB, Sinha S, Arunodaya GR, Srikanth SG. Neurological pictures. Hypomelanosis of Ito. J Neurol Neurosurg Psychiatry. 2006 Jul;77(7):873.
- Bhardwaj M, Vashisht N. Hypomelanosis of Ito. Indian Pediatr. 2004 Apr;41(4):401.
- Moss C, Larkins S, Stacey M, Blight A, Farndon PA, Davison EV. Epidermal mosaicism and Blaschko's lines. J Med Genet. 1993 Sep;30(9):752-5.