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Diseases

Genetic and Rare Diseases Information Center (GARD)

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Serpiginous choroiditis


Other Names for this Disease
  • Geographic choroiditis
  • Geographic helicoid peripapillary choroidopathy (GHPC)
  • Geographic serpiginous choroiditis
  • Peripapillary choriopathy
  • Serpiginous choroidopathy
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Overview



What is serpiginous choroiditis?

What causes serpiginous choroiditis?


What is serpiginous choroiditis?

Serpiginous choroiditis is a rare inflammatory eye condition that typically develops between age 30 and 70 years.[1] Affected individuals have lesions in the eye that last from weeks to months and involve scarring of the eye tissue.[2] Recurrence of these lesions is common in serpiginous choroiditis. Vision loss may occur in one or both eyes when the macula is involved. [3] Treatment options involve anti-inflammatory and immune-suppressing medications.[1][3]
Last updated: 9/16/2013

What causes serpiginous choroiditis?

The cause of serpiginous choroiditis is unknown.[3][4] Speculation exists regarding an association with exposure to various toxic compounds and/or infectious agents.[3][5] Some researchers believe the condition is related to an organ-specific autoimmune inflammatory process.[6]
Last updated: 9/16/2013

References
  1. Serpiginous choroiditis. Digital Reference of Ophthalmology. http://dro.hs.columbia.edu/serpiginous.htm. Accessed 9/16/2013.
  2. Da Mata AP. Serpiginous Choroiditis. Ocular Immunology and Uveitis Foundation. February 1998; http://www.uveitis.org/docs/dm/serpiginous_chroiditis.pdf. Accessed 9/16/2013.
  3. Tewari A, Eliott D. White Dot Syndromes. Medscape Reference. December 19, 2007; http://emedicine.medscape.com/article/1227778-overview. Accessed 9/16/2013.
  4. Choroiditis, Serpiginous. National Organization for Rare Disorders (NORD). 2003; http://www.rarediseases.org/rare-disease-information/rare-diseases/byID/1011/viewAbstract. Accessed 9/16/2013.
  5. Gupta A, Biswas J. Serpiginous choroiditis and acute retinal necrosis occurring in the same patient. Indian J Ophthalmol. 2003; http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744787/. Accessed 9/16/2013.
  6. Khanamiri N, Rao NA. Serpiginous choroiditis and infectious multifocal serpiginoid choroiditis. Surv Ophthalmol. 2013; http://www.ncbi.nlm.nih.gov/pubmed/23541041. Accessed 9/16/2013.