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Long QT syndrome 1

Other Names for this Disease
  • LQT1
  • Romano-Ward syndrome
  • Ventricular fibrillation with prolonged QT interval
  • Ward-Romano syndrome
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Romano-Ward syndrome is the most common form of inherited long QT syndrome. Symptoms include arrhythmia, fainting, cardiac arrest, and sudden death. There are six different types of this syndrome, long QT 1 through 6. Each type is caused by a change in a different gene. The most prevalent form of long QT syndrome is long QT type 1. Long QT type 1 is caused by changes in the KCNQ1 gene. Romano-Ward syndrome is inherited in an autosomal dominant fashion.[1]
Last updated: 4/15/2011


  1. Sovari AA, Kocheril AG, Assadi R Baas AS, Zareba W, Rosero S. Long QT syndrome. eMedicine. 2010; . Accessed 4/15/2011.
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Basic Information

  • Genetics Home Reference (GHR) contains information on Long QT syndrome 1. This website is maintained by the National Library of Medicine.
  • The National Organization for Rare Disorders (NORD) is a federation of more than 130 nonprofit voluntary health organizations serving people with rare disorders. Click on the link to view information on this topic.
  • The Madisons Foundation has developed an information page on Romano-Ward syndrome. Click on Madisons Foundation to view the page.

In Depth Information

  • Medscape Reference provides information on this topic. Click on the link to view this information. You may need to register to view the medical textbook, but registration is free.
  • MeSH® (Medical Subject Headings) is a terminology tool used by the National Library of Medicine. Click on the link to view information on this topic.
  • The Online Mendelian Inheritance in Man (OMIM) is an catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine. 
  • Orphanet is a European reference portal for information on rare diseases and orphan drugs.  Access to this database is free of charge.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Long QT syndrome 1. Click on the link to view a sample search on this topic.