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Genetic and Rare Diseases Information Center (GARD)

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Hereditary lymphedema type II


Other Names for this Disease
  • Lymphedema hereditary type 2
  • Lymphedema praecox
  • Lymphedema, hereditary, II
  • Lymphedema, late-onset
  • Meige disease
More Names
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Overview


Hereditary lymphedema type II is a primary lymphedema that results from abnormal transport of lymph fluid. Individuals with this condition usually develop swelling in the lower legs and feet during puberty. Some affected individuals develop a non-contagious skin infection called cellulitis, which can further damage the lymphatic vessels (the thin tubes that carry lymph fluid). While the cause of hereditary lymphedema type II is unknown, it is thought to be genetic because it tends to run in families. It appears to have an autosomal dominant pattern of inheritance.[1]
Last updated: 2/9/2012

References

  1. Meige lymphedema. Genetics Home Reference (GHR). November 2010; http://ghr.nlm.nih.gov/condition/meige-lymphedema. Accessed 2/9/2012.
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Basic Information

  • Genetics Home Reference (GHR) contains information on Hereditary lymphedema type II. This website is maintained by the National Library of Medicine.
  • MedlinePlus was designed by the National Library of Medicine to help you research your health questions, and it provides more information about this topic.
  • The National Organization for Rare Disorders (NORD) is a federation of more than 130 nonprofit voluntary health organizations serving people with rare disorders. Click on the link to view information on this topic.

In Depth Information

  • Medscape Reference provides information on this topic. Click on the link to view this information. You may need to register to view the medical textbook, but registration is free.
  • The Online Mendelian Inheritance in Man (OMIM) is an catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine. 
  • Orphanet is a European reference portal for information on rare diseases and orphan drugs.  Access to this database is free of charge.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Hereditary lymphedema type II. Click on the link to view a sample search on this topic.