Your browser does not support javascript:   Search for gard hereSearch for news-and-events here.

Diseases

Genetic and Rare Diseases Information Center (GARD)

Print friendly version

Melanoma, familial


See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Treatment

Medical Products

The medication(s) listed in the table(s) below have been approved by the Food and Drug Administration (FDA) for treatment of this condition. The FDA Office of Orphan Products Development designates "orphan products" for those that treat rare diseases affecting fewer than 200,000 Americans. The table(s) below may not be an exhaustive list of drugs or products used to treat this condition. There may be other products available that are not considered orphan products. To search for all FDA approved drugs, visit Drugs@FDA. You can find orphan products used to treat other conditions by searching the Orphan Drug Product Designation database.


Generic Name pembrolizumab
Trade Name
(Manufacturer Name)
Keytruda
(Merck, Sharp & Dohme Corp)
Indication
The FDA has approved this product to be used in this manner.
Treatment of patients with unresectable or metastatic melanoma and disease progression following ipilimumab and, if BRAF V600 mutation positive, a BRAF inhibitor.
More Information about this product Drug Information Portal

Generic Name Trametinib
Trade Name
(Manufacturer Name)
Mekinist
(GlaxoSmithKline, LLC)
Indication
The FDA has approved this product to be used in this manner.
Treatment of patients with unresectable or metastatic melanoma with BRAF V600E or V600K mutations as detected by an FDA approved test.
More Information about this product Drug Information Portal

Generic Name Aldesleukin
Trade Name
(Manufacturer Name)
Proleukin
(Novartis)
Indication
The FDA has approved this product to be used in this manner.
Treatment of adults with metastatic melanoma.

Generic Name Peginterferon Alfa-2b
Trade Name
(Manufacturer Name)
Sylatron
(Schering/Merck)
Indication
The FDA has approved this product to be used in this manner.
Adjuvant treatment of melanoma with microscopic or gross nodal involvement within 84 days of definitive surgical resection including complete lymphadenectomy
More Information about this product Drug Information Portal

Generic Name Dabrafenib
Trade Name
(Manufacturer Name)
Tafinlar
(GlaxoSmithKline, LLC)
Indication
The FDA has approved this product to be used in this manner.
Treatment of patients with unresectable or metastatic melanoma with BRAF V600E mutation as detected by an FDA approved test.
More Information about this product Drug Information Portal

Generic Name Technetium Tc99m sulfur colloid injection, lyophilized
Trade Name
(Manufacturer Name)
Technetium Tc99m Sulfur Colloi
(Pharmalucence, Inc.)
Indication
The FDA has approved this product to be used in this manner.
Localization of lymph nodes draining a primary tumor in patients with melanoma when used with a hand-held gamma counter
More Information about this product Drug Information Portal

Generic Name Ipilimumab
Trade Name
(Manufacturer Name)
Yervoy
(Bristol-Myers Squibb Pharmaceutical)
Indication
The FDA has approved this product to be used in this manner.
Treatment of unresectable or metastatic melanoma.
More Information about this product Drug Information Portal

See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.