Multiple endocrine neoplasia type 1
Other Names for this Disease
- Endocrine adenomatosis multiple
- MEN 1
- Wermer syndrome
parathyroid gland, the pituitary gland, and the pancreas, although other glands may be involved as well. These tumors are often "functional" and secrete excess hormones, which can cause a variety of health problems. The most common signs and symptoms of MEN1 are caused by hyperparathyroidism (overactive parathyroid gland) and may include kidney stones; thinning of bones; nausea and vomiting; high blood pressure (hypertension); weakness; and fatigue. MEN1 is caused by changes (mutations) in the MEN1 gene and is inherited in an autosomal dominant manner. Management for MEN1 usually includes regular screening to allow for early diagnosis and treatment of endocrine tumors.Multiple endocrine neoplasia, type 1 (MEN1) is an inherited condition that causes tumors of the endocrine system (the body's network of hormone-producing glands). People affected by MEN1 typically develop tumors of the
Last updated: 11/26/2014
- Multiple Endocrine Neoplasia. Genetic Home Reference. August 2013; http://ghr.nlm.nih.gov/condition/multiple-endocrine-neoplasia.
- Pagon RA, Adam MP, Ardinger HH, et al. Multiple Endocrine Neoplasia Type 1. GeneReviews. September 2012; http://www.ncbi.nlm.nih.gov/books/NBK1538/?report=printable.
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