X-linked myopathy with excessive autophagy
Other Names for this Disease
- Myopathy, X-linked, with excessive autophagy
- Vacuolar myopathy
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mutations in the VMA21 gene and is inherited in an X-linked recessive fashion.X-Linked Myopathy with Excessive Autophagy (XMEA) is a type of inherited myopathy (muscle disease) that mainly affects males. It is characterized by muscle weakness that slowly worsens over time. Weakness involving the upper legs, affecting activities such as running and climbing stairs, may be noticed first. As the condition progresses, men with XMEA may experience weakness in their lower legs and arms. Some people with XMEA remain able to walk in advanced age, while others require assistance in adulthood. It is caused by
Last updated: 10/10/2011
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- The Muscular Dystrophy Association has developed a resource called "Facts About Myopathies" that discusses commonly asked questions regarding myopathies. Click on the link above to view this information page.
- Online Mendelian Inheritance in Man (OMIM) is a catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine.
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