Your browser does not support javascript:   Search for gard hereSearch for news-and-events here.

Diseases

Genetic and Rare Diseases Information Center (GARD)

Print friendly version

Inclusion body myositis


Other Names for this Disease
  • IBM
  • Inflammatory myopathy
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Overview


Inclusion body myositis (IBM) is an inflammatory myopathy that is characterized by chronic, progressive muscle inflammation and muscle weakness. Symptoms usually begin after the age of 50, although the condition can occur earlier. The onset of muscle weakness usually occurs over months or years. This condition affects both the proximal (close to the trunk of the body) and distal (further away from the trunk) muscles. There is currently no effective treatment for IBM.[1] The cause is unclear in most cases, but it can sometimes be inherited.[2]
Last updated: 4/22/2011

References

  1. NINDS Inclusion Body Myositis Information Page. National Institute of Neurological Disorders and Stroke. National Institute of Neurological Disorders and ; http://www.ninds.nih.gov/disorders/inclusion_body_myositis/inclusion_body_myositis.htm. Accessed 4/22/2011.
  2. Inclusion Body Myositis (IBM). Muscular Dystrophy Association. 2011; http://www.mda.org/disease/ibm.html. Accessed 4/22/2011.
Your Questions Answered
by the Genetic and Rare Diseases Information Center

Please contact us with your questions about Inclusion body myositis. We will answer your question and update these pages with new resources and information.

Basic Information

  • The Muscular Dystrophy Association has a Web page on inclusion body myositis. Click on the link to view this information.
  • MedlinePlus was designed by the National Library of Medicine to help you research your health questions, and it provides more information about this topic.
  • The National Institute of Neurological Disorders and Stroke (NINDS) collects and disseminates research information related to neurological disorders. Click on the link to view information on this topic.
  • The Muscular Dystrophy Association has developed a resource called "Facts About Myopathies" that discusses commonly asked questions regarding myopathies. Click on the link above to view this information page.

In Depth Information

  • Medscape Reference provides information on this topic. Click on the link to view this information. You may need to register to view the medical textbook, but registration is free.
  • The Online Mendelian Inheritance in Man (OMIM) is an catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine. 
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Inclusion body myositis. Click on the link to view a sample search on this topic.