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Genetic and Rare Diseases Information Center (GARD)

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Amniotic band syndrome

Other Names for this Disease
  • ABS
  • Amniotic bands sequence
  • Congenital constricting bands
  • Familial amniotic bands
  • Streeter anomaly
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What are the signs and symptoms of amniotic band syndrome?

The symptoms of amniotic band syndrome depend on the severity and location of the constrictions. The mildest constrictions affect only the superficial skin and may not require treatment. Deeper constrictions may block lymphatic vessels, impair blood flow, and require immediate surgical care.[1] When the bands affect the limbs, the lower part of the limbs are most often involved, especially the middle, long, and index fingers of the hand. When the feet are involved, the bands most commonly affect the big toe.[1]

Pressure from the bands may result in additional abnormalities, such as underdevelopment of a limb, bone abnormalities, amputations, leg-length discrepancy, and club feet. Constriction bands across the head and face may lead to facial clefts. Severe clefts affecting vital organs are often life-threatening.[1]

Last updated: 11/1/2013

  1. Do T. Streeter Dysplasia. Medscape Reference. February 7, 2012; Accessed 11/1/2013.