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Catecholaminergic polymorphic ventricular tachycardia

Other Names for this Disease
  • Bidirectional tachycardia induced by catecholamine
  • Catecholamine-induced polymorphic ventricular tachycardia
  • CVPT
  • Double tachycardia induced by catecholamines
  • Familial polymorphic ventricular tachycardia
More Names
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Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a genetic disorder that causes an abnormally fast and irregular heart rhythm in response to physical activity or emotional stress. Signs and symptoms include light-headedness, dizziness, and fainting. If untreated CPVT can cause a heart attack and death. CPVT is caused by mutations in the RYR2 or CASQ2 genes. When a RYR2 gene mutation is involved, the condition is passed through families in an autosomal dominant fashion. When CASQ2 gene mutations are involved, the condition is inherited in an autosomal recessive fashion.[1] In some cases the underlying cause can not be determined.
Last updated: 1/25/2013


  1. Catecholaminergic polymorphic ventricular tachycardia. Genetics Home Reference. December 2009; Accessed 1/25/2013.
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