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Genetic and Rare Diseases Information Center (GARD)

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Other Names for this Disease
  • Familial Testotoxicosis (subtype)
  • Precocious puberty, male limited
  • Pubertas Praecox
  • Sexual precocity, familial, gonadotropin-independent
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Your Questions Answered

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  • My uncle, my brother, and one of my brother's sons have testotoxicosis. My son is also affected. I took my son to an endocrinologist and he treated my son with ketoconazole. Treatment was stopped when my son was 11 years old. He continued to grow until the age of 13. Now he is 14 and is 5'7".  We are in the process of going back to the doctor that treated my son to get an x-ray of his hand to see if the growth plates have grown together. Has ketoconazole been proven to work successfully in boys with testotoxicosis? Click here for answer