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Diseases

Genetic and Rare Diseases Information Center (GARD)

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Complex regional pain syndrome


Other Names for this Disease

  • CRPS
  • Reflex sympathetic dystrophy syndrome
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Cause

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What causes complex regional pain syndrome?

Currently the cause of complex regional pain syndrome is not well understood. In general it is thought to be caused by damage to the nervous system such as by injury or infection in an arm or leg, heart attack, or stroke. This damage includes harm to the nerves that control the blood vessels and sweat glands.[1] A second theory is that this syndrome is caused by a triggering of the immune response, which leads to the characteristic inflammatory symptoms of redness, warmth, and swelling in the affected area.[2]
Last updated: 10/19/2011

References
  1. Complex regional pain syndrome. MedlinePlus. 2008; http://www.nlm.nih.gov/medlineplus/ency/article/007184.htm. Accessed 5/20/2009.
  2. NINDS Complex regional pain syndrome information page. National Institute of Neurological Disorders and Stroke. April 2011; http://www.ninds.nih.gov/disorders/reflex_sympathetic_dystrophy/reflex_sympathetic_dystrophy.htm. Accessed 10/19/2011.


Other Names for this Disease
  • CRPS
  • Reflex sympathetic dystrophy syndrome
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.