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Diseases

Genetic and Rare Diseases Information Center (GARD)

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Complex regional pain syndrome


Other Names for this Disease

  • CRPS
  • Reflex sympathetic dystrophy
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Cause

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What causes complex regional pain syndrome?

The underlying cause of complex regional pain syndrome (CRPS) is not well understood. In most cases it occurs occurs after an illness or injury that did not directly damage the nerves in the affected area. In some cases, it occurs after a specific nerve injury. The exact trigger of CRPS after an injury is not known, but it may be due to abnormal interactions between the central and peripheral nervous systems, and/or inappropriate inflammatory responses.[1]
Last updated: 11/11/2014

References
  1. Complex regional pain syndrome. Mayo Clinic. http://www.mayoclinic.org/diseases-conditions/complex-regional-pain-syndrome/basics/definition/con-20022844. Accessed 11/11/2014.


Other Names for this Disease
  • CRPS
  • Reflex sympathetic dystrophy
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.