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Diseases

Genetic and Rare Diseases Information Center (GARD)

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Complex regional pain syndrome


Other Names for this Disease

  • CRPS
  • Reflex sympathetic dystrophy
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Treatment

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How might complex regional pain syndrome be treated?

There is no known cure for complex regional pain syndrome (CRPS). Treatment mainly aims to control painful symptoms. If treatment is started within a few months of when symptoms begin, improvement or remission may be possible. A combination of therapies is usually necessary. Medications used to treat CRPS may include oral and topical pain relievers; antidepressants or anticonvulsants (which are sometimes used to treat pain); corticosteroids; bone-loss medications; sympathetic nerve-blocking medications; and/or intravenous anesthetics. Other therapies used may include applying heat or cold; physical therapy; electrical nerve stimulation; biofeedback; and/or spinal cord stimulation.[1] Unfortunately, no single drug or therapy (or combination) has shown consistent, long-lasting improvement among affected people.[2]
Last updated: 11/11/2014

References
  1. Complex regional pain syndrome. Mayo Clinic. http://www.mayoclinic.org/diseases-conditions/complex-regional-pain-syndrome/basics/definition/con-20022844. Accessed 11/11/2014.
  2. NINDS Complex Regional Pain Syndrome Information Page. NINDS. September 26, 2014; http://www.ninds.nih.gov/disorders/reflex_sympathetic_dystrophy/reflex_sympathetic_dystrophy.htm. Accessed 11/10/2014.


Clinical Trials & Research for this Disease

  • ClinicalTrials.gov lists trials that are studying or have studied Complex regional pain syndrome. Click on the link to go to ClinicalTrials.gov to read descriptions of these studies.
Other Names for this Disease
  • CRPS
  • Reflex sympathetic dystrophy
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.