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Genetic and Rare Diseases Information Center (GARD)

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Russell-Silver syndrome


Other Names for this Disease

  • Silver-Russell dwarfism
  • Silver-Russell syndrome
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Overview

Russell-Silver syndrome is a condition present at birth that involves poor growth, low birth weight, short height, and size differences (asymmetry) of parts of the body.[1] Other signs and symptoms may include poor appetite; low blood sugar (hypoglycemia) as a result of feeding difficulties; a small, triangular face with distinctive facial features; clinodactyly; digestive system abnormalities; delayed development; and/or learning disabilities. The genetic causes of this syndrome are complex and relate to certain genes that control growth. Most cases are not inherited from an affected parent, but occur sporadically (i.e., by chance). In some cases, it is inherited in an autosomal dominant or autosomal recessive manner.[2]
Last updated: 2/11/2014

References

  1. Russell-Silver syndrome. MedlinePlus. 2010; http://www.nlm.nih.gov/medlineplus/ency/article/001209.htm. Accessed 11/30/2011.
  2. Russell-Silver syndrome. Genetics Home Reference. 2008; http://ghr.nlm.nih.gov/condition=russellsilversyndrome. Accessed 11/30/2011.
Your Questions Answered
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5 question(s) from the public on Russell-Silver syndrome have been answered. See questions and answers. You can also submit a new question.

Basic Information

  • Genetics Home Reference (GHR) contains information on Russell-Silver syndrome. This website is maintained by the National Library of Medicine.
  • The MAGIC Foundation has an information page on Russell-Silver syndrome. Click on MAGIC Foundation to view the information page.
  • MedlinePlus was designed by the National Library of Medicine to help you research your health questions, and it provides more information about this topic.
  • The National Organization for Rare Disorders (NORD) is a federation of more than 130 nonprofit voluntary health organizations serving people with rare disorders. Click on the link to view information on this topic.

In Depth Information

  • Medscape Reference provides information on this topic. Click on the link to view this information. You may need to register to view the medical textbook, but registration is free.
  • The Online Mendelian Inheritance in Man (OMIM) is an catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine. 
  • Orphanet is a European reference portal for information on rare diseases and orphan drugs.  Access to this database is free of charge.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Russell-Silver syndrome. Click on the link to view a sample search on this topic.
Other Names for this Disease
  • Silver-Russell dwarfism
  • Silver-Russell syndrome
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.