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Spinocerebellar ataxia 8
Other Names for this Disease
- Spinocerebellar ataxia type 8
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neurodegenerative condition characterized by slowly progressive ataxia (problems with movement, balance, and coordination). This condition typically occurs in adulthood and usually progresses over decades. Common initial symptoms include dysarthria, slow speech, and trouble walking. Some affected individuals experience nystagmus and other abnormal eye movements. Life span is typically not shortened. This condition is inherited in an autosomal dominant manner, although not all individuals with abnormalities in the disease-causing gene will develop the disease (called reduced penetrance).Spinocerebellar ataxia type 8 (SCA8) is an inherited
Last updated: 1/2/2012
- Ikeda Y, Dalton JC, Day JW & Ranum LPW. Spinocerebellar Ataxia Type 8. GeneReviews. February 2007; http://www.ncbi.nlm.nih.gov/books/NBK1268/. Accessed 10/12/2011.
- Yoshio Ikeda, Joline C Dalton, John W Day, Laura PW Ranum. Spinocerebellar Ataxia Type 8. GeneReviews. February 7, 2007; http://www.ncbi.nlm.nih.gov/books/NBK1268/. Accessed 1/2/2011.
- The National Ataxia Foundation provides an information pamphlet in spinocerebellar ataxia type 8. To view this information, click on the link above.
- The National Center for Biotechnology Information (NCBI) was established in 1988 as a national resource for molecular biology information. Click on the link to view information on this topic.
- The National Institute of Neurological Disorders and Stroke (NINDS) collects and disseminates research information related to neurological disorders. Click on the link to view information on this topic.
- Spinocerebellar Ataxia: Making an Informed Choice about Genetic Testing is a booklet providing information about spinocerebellar ataxia and is available as a PDF document on the University of Washington Medical Center Web site. Click on the title above to view this resource.
In Depth Information
- The Online Mendelian Inheritance in Man (OMIM) is an catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine.
- Orphanet is a European reference portal for information on rare diseases and orphan drugs. Access to this database is free of charge.
- PubMed is a searchable database of medical literature and lists journal articles that discuss Spinocerebellar ataxia 8. Click on the link to view a sample search on this topic.
- The Social Security Administration has included this condition in their Compassionate Allowances Initiative. This initiative speeds up the processing of disability claims for applicants with certain medical conditions that cause severe disability. More information about Compassionate Allowances and applying for Social Security disability is available online.