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Genetic and Rare Diseases Information Center (GARD)

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Acute febrile neutrophilic dermatosis


Other Names for this Disease
  • Gomm Button disease
  • Neutrophilic dermatosis, acute febrile
  • SS
  • Sweet syndrome
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Overview


Acute febrile neutrophilic dermatosis - also known as Sweet syndrome - is a skin condition marked by fever, inflammation of the joints (arthritis), and painful skin lesions that appear mainly on the face, neck, back and arms.[1][2] Although middle-aged women are most likely to develop this condition, it may also affect men, older adults and even infants. The exact cause of acute febrile neutrophilic dermatosis often isn't known. In some people, it's triggered by an infection, illness or certain medications. This condition can also occur with some types of cancer and other serious health problems. Most often, it isn't serious and will clear on its own in a few months. Healing is much more rapid, however, with treatment.[1]
Last updated: 7/23/2009

References

  1. Sweet syndrome. MayoClinic.com. 2008; http://www.mayoclinic.com/print/sweets-syndrome/DS00752/DSECTION=all&METHOD=print. Accessed 7/23/2009.
  2. Sweet Syndrome. National Organization for Rare Disorders (NORD). 2002; http://www.rarediseases.org/search/rdbdetail_abstract.html?disname=Sweet%20Syndrome. Accessed 7/23/2009.
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Basic Information

  • DermNet NZ is an online resource about skin diseases developed by the New Zealand Dermatological Society Incorporated. DermNet NZ provides information about this condition.
  • The Doctor's Doctor web site provides information about acute febrile neutrophilic dermatosis. Click on the link to access this information.
  • The MayoClinic.com provides information about acute febrile neutrophilic dermatosis. Click on the link to access this information.
  • The Merck Manuals Online Medical Library provides information on this condition. Click on the link to view the information.
  • The National Organization for Rare Disorders (NORD) is a federation of more than 130 nonprofit voluntary health organizations serving people with rare disorders. Click on the link to view information on this topic.

In Depth Information

  • Medscape Reference provides information on this topic. Click on the link to view this information. You may need to register to view the medical textbook, but registration is free.
  • The Online Mendelian Inheritance in Man (OMIM) is an catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine. 
  • Orphanet is a European reference portal for information on rare diseases and orphan drugs.  Access to this database is free of charge.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Acute febrile neutrophilic dermatosis. Click on the link to view a sample search on this topic.