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Multiple familial trichoepithelioma 1


Other Names for this Disease
  • MFT1
  • Trichoepithelioma multiple familial 1
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Overview


Multiple familial trichoepithelioma is a rare condition characterized by multiple smooth, round, firm, skin-colored papules that usually occur on the face, but may also occur on the scalp, neck, and trunk.[1][2] The lesions are derived from immature hair follicles.[2] They may get bigger over time, but they usually do not ulcerate.[1] Treatment often involves surgery to remove a single lesion and cryosurgery or laser surgery for multiple ones.[1] It is caused by a mutation in the CYLD gene. It is inherited in an autosomal dominant fashion.
Last updated: 8/30/2009

References

  1. Neff AG, Carter KD. Benign Eyelid Lesions. In: Yanoff & Duker. Ophthalmology, 3rd ed. Philadelphia, PA: Mosby; 2008;
  2. Morelli JG. Tumors of the Skin. In: Kliegman eds. Nelson Textbook of Pediatrics, 18th ed. Philadelphia, PA: Saunders; 2007;
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Basic Information

  • DermNet NZ is an online resource about skin diseases developed by the New Zealand Dermatological Society Incorporated. DermNet NZ provides information about this condition.
  • Genetics Home Reference (GHR) contains information on Multiple familial trichoepithelioma 1. This website is maintained by the National Library of Medicine.
  • MedlinePlus provides more information on skin conditions in general. MedlinePlus is a Web site designed by the National Library of Medicine to help you research your health questions.

In Depth Information

  • Medscape Reference provides information on this topic. Click on the link to view this information. You may need to register to view the medical textbook, but registration is free.
  • The Online Mendelian Inheritance in Man (OMIM) is an catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine. 
  • Orphanet is a European reference portal for information on rare diseases and orphan drugs.  Access to this database is free of charge.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Multiple familial trichoepithelioma 1. Click on the link to view a sample search on this topic.

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