Acute promyelocytic leukemia
What causes acute promyelocytic leukemia?
Is acute promyelocytic leukemia inherited?
How might acute promyelocytic leukemia be treated?
Patients who cannot tolerate an anthracycline drug may get ATRA plus another drug called arsenic trioxide. Arsenic trioxide has also proven to be an effective alternative for the 20% to 30% of patients with APL who don't respond to initial treatment or who relapse. If treatment with arsenic trioxide achieves a remission, further courses of this drug may be given. An autologous stem cell transplant may also be an option. If a second remission is not achieved, treatment options may include an allogeneic stem cell transplant or taking part in a clinical trial.
- General Information About Adult Myeloid Leukemia. National Cancer Institute (NCI). 2009; http://www.cancer.gov/cancertopics/pdq/treatment/adultAML/Patient#Keypoint2. Accessed 6/23/2011.
- Acute promyelocytic leukemia. Genetics Home Reference (GHR). April 2011; http://ghr.nlm.nih.gov/condition/acute-promyelocytic-leukemia. Accessed 6/23/2011.
- Acute promyelocytic leukemia. Genetics Home Reference. April 2011; http://ghr.nlm.nih.gov/condition/acute-promyelocytic-leukemia. Accessed 2/6/2012.
- Treatment of acute promyelocytic (M3) leukemia. American Cancer Society. December 2010; http://www.cancer.org/Cancer/Leukemia-AcuteMyeloidAML/DetailedGuide/leukemia-acute-myeloid-myelogenous-treating-m3-leukemia. Accessed 6/23/2011.
- What if the leukemia doesn`t respond or comes back after treatment?. American Cancer Society. December 2010; http://www.cancer.org/Cancer/Leukemia-AcuteMyeloidAML/DetailedGuide/leukemia-acute-myeloid-myelogenous-treating-recurrence. Accessed 6/23/2011.