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Acute promyelocytic leukemia

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Overview


Acute promyelocytic leukemia is an aggressive type of acute myeloid leukemia in which there are too many immature blood-forming cells in the blood and bone marrow.[1][2] It is usually marked by a translocation of chromosomes 15 and 17.[2] Acute promyelocytic leukemia usually occurs in middle-aged adults. Symptoms may include both bleeding and forming blood clots.[1]


References

  1. General Information About Adult Myeloid Leukemia. National Cancer Institute (NCI). http://www.cancer.gov/cancertopics/pdq/treatment/adultAML/Patient#Keypoint2. Accessed June 23, 2011.
  2. Acute promyelocytic leukemia. Genetics Home Reference (GHR). http://ghr.nlm.nih.gov/condition/acute-promyelocytic-leukemia. Accessed June 23, 2011.
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General Information

  • Genetics Home Reference (GHR) contains information on Acute promyelocytic leukemia. Click on the link to go to GHR and review the information.
  • Medscape Reference provides information on this topic. Click on the link to view this information. You may need to register to view the medical textbook, but registration is free.
  • The National Cancer Institute provides the most current information on cancer for patients, health professionals, and the general public.  Click on the link to view information on this topic. 
  • Orphanet is a European reference portal for information on rare diseases and orphan drugs.  Access to this database is free of charge.  Click on the link to read information on this topic.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Acute promyelocytic leukemia. Click on the link to view a sample search on this topic.
  • The The Online Mendelian Inheritance in Man (OMIM) database contains genetics resources that discuss Acute promyelocytic leukemia. Click on the link to go to OMIM and review these resources.