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Genetic and Rare Diseases Information Center (GARD)

Other Names for this Disease
  • Pancreatic VIPoma
  • Vasoactive intestinal peptide (VIP) tumor
  • Vasoactive intestinal peptide-producing tumor
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VIPoma is a rare cancer that develops within the pancreas. This tumor causes pancreatic cells to produce high levels of a hormone called vasoactive intestinal peptide (VIP). The signs and symptoms of a VIPoma include abdominal pain, flushing or redness of the face, nausea, watery diarrhea, weight loss, dehydration, and low blood potassium (hypokalemia). VIPomas are usually diagnosed in adults around age 50. The cause of VIPoma is unknown. Treatment may include intravenous (IV) fluids to correct dehydration, medications such as octreotide to help control diarrhea, and surgery to remove the tumor.[1]
Last updated: 3/8/2010


  1. Stitham SO. VIPoma. MedlinePlus Web site. September 4, 2008; Accessed 3/8/2010.
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Basic Information

  • MedlinePlus was designed by the National Library of Medicine to help you research your health questions, and it provides more information about this topic.
  • The Merck Manuals Online Medical Library provides information on this condition. Click on the link to view the information.

In Depth Information

  • Orphanet is a European reference portal for information on rare diseases and orphan drugs.  Access to this database is free of charge.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss VIPoma. Click on the link to view a sample search on this topic.
  • eMedicine has two articles on this topic from the perspective of Endocrinology and Pediatrics. You may need to register to view the information online, but registration is free. Click on the links above to view the articles from this medical reference Web site.