Other Names for this Disease
- Very long chain acyl-CoA dehydrogenase deficiency
- Very long-chain acyl-CoA dehydrogenase deficiency
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.
On this page
VLCAD deficiency is inherited in an autosomal recessive manner. This means that both copies of the disease-causing gene (one inherited from each parent) must have a mutation in order to cause signs and symptoms of the condition. An individual who has one mutated copy of the gene and one normal copy is referred to as a carrier. Carriers usually do not have signs or symptoms of the condition. When two carrier parents have children, each child has a 25% (1 in 4) risk to be affected, a 50% (1 in 2) risk to be a carrier like each parent, and a 25% risk to be unaffected and not a carrier.
Last updated: 12/10/2013