Your browser does not support javascript:   Search for gard hereSearch for news-and-events here.

Diseases

Genetic and Rare Diseases Information Center (GARD)

Print friendly version

Adie syndrome


Other Names for this Disease

  • Adie's Pupil
  • HAS
  • Holmes-Adie syndrome
  • Tonic, sluggishly reacting pupil and hypoactive or absent tendon reflexes
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Overview

Adie syndrome is is a neurological disorder affecting the pupil of the eye and the autonomic nervous system.  It is characterized by one eye with a pupil that is larger than normal that constricts slowly in bright light (tonic pupil), along with the absence of deep tendon reflexes, usually in the Achilles tendon. Adie syndrome may be the result of a viral or bacterial infection that causes inflammation and damage to neurons in the ciliary ganglion, an area of the brain that controls eye movements, and the spinal ganglion, an area of the brain involved in the response of the autonomic nervous system.[1] Most cases of Adie Syndrome are not progressive, life threatening, or disabling.[1][2]  
Last updated: 5/3/2010

References

  1. NINDS Holmes-Adie syndrome Information Page. National Institute of Neurological Disorders and Stroke (NINDS). February 13, 2007; http://www.ninds.nih.gov/disorders/holmes_adie/holmes_adie.htm. Accessed 5/3/2010.
  2. Adie Syndrome. National Organization for Rare Disorders (NORD). 2007; http://www.rarediseases.org/search/rdbdetail_abstract.html?disname=Adie%20Syndrome. Accessed 5/3/2010.
Your Questions Answered
by the Genetic and Rare Diseases Information Center

1 question(s) from the public on Adie syndrome have been answered. See questions and answers. You can also submit a new question.

Basic Information

In Depth Information

  • Medscape Reference provides information on this topic. Click on the link to view this information. You may need to register to view the medical textbook, but registration is free.
  • The Online Mendelian Inheritance in Man (OMIM) is an catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine. 
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Adie syndrome. Click on the link to view a sample search on this topic.
Other Names for this Disease
  • Adie's Pupil
  • HAS
  • Holmes-Adie syndrome
  • Tonic, sluggishly reacting pupil and hypoactive or absent tendon reflexes
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.