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Diseases

Genetic and Rare Diseases Information Center (GARD)

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Adiposis dolorosa


Other Names for this Disease
  • Dercum disease
  • Dercum's disease
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Inheritance


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Is adiposis dolorosa inherited?

Most cases of adiposis dolorosa are sporadic. This means that it usually occurs in an individual with no history of the condition in his/her family. Adiposis dolorosa has rarely been reported to occur in more than one family member; in some of these cases, it appears to have been inherited in an autosomal dominant manner. This means that when an affected individual has children, each child has a 50% (1 in 2) risk to inherit the gene causing the condition. However, no associated genes have been identified.[1][2]
Last updated: 11/11/2013

References
  1. Learning about Dercum Disease. National Human Genome Research Institute. July 2010; http://www.genome.gov/17516629. Accessed 5/13/2011.
  2. Adiposis dolorosa. Genetics Home Reference. July, 2012; http://ghr.nlm.nih.gov/condition/adiposis-dolorosa. Accessed 11/11/2013.