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Genetic and Rare Diseases Information Center (GARD)

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Adiposis dolorosa

Other Names for this Disease
  • Dercum disease
  • Dercum's disease
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How might adiposis dolorosa be treated?

There is no cure for adiposis dolorosa. At the present time, treatment for this condition is symptomatic, meaning that it focuses on addressing each symptom of the condition rather than the underlying cause (which remains unknown). Depending on the person, options can include weight reduction, surgery for painful lipomas, and medications to control pain. Liposuction has been used in some cases.[1]

Pain can sometimes be relieved by injections of steroids such as prednisone or intravenous lidocaine. Interferon alpha 2b for pain relief is being explored as a therapy for some people. Traditional pain relievers, such as aspirin or ibuprofen, usually are not very efficient.[2] 

An article from Medscape Reference provides additional information on treatment for adiposis dolorosa. You may need to register to view the article, but registration is free.
Last updated: 11/11/2013

  1. Learning about Dercum Disease. National Human Genome Research Institute. July 2010; Accessed 5/13/2011.
  2. Marjan Yousefi, M.D. . Adiposis Dolorosa Treatment & Management. eMedicine. November 2007; Accessed 5/13/2011.

Clinical Trials & Research for this Disease

  • The Centers for Mendelian Genomics program is working to discover the causes of rare genetic disorders. For more information about applying to the research study, please visit their website.