Other Names for this Disease
- Afibrinogenemia congenital
- Congenital afibrinogenemia
Afibrinogenemia, sometimes called congenital afibrinogenemia, is an inherited blood disorder in which the blood does not clot normally. It occurs when there is a lack (deficiency) of a protein called fibrinogen (or factor I), which is needed for the blood to clot. Affected individuals may be susceptible to severe bleeding (hemorrhaging) episodes, particularly during infancy and childhood. Afibrinogenemia is thought to be transmitted as an autosomal recessive trait.
- Dugdale DC, Chen YB. Congenital afibrinogenemia. MedlinePlus. 2009; http://www.nlm.nih.gov/medlineplus/ency/article/001313.htm. Accessed 7/17/2009.
- Afibrinogenemia, Congenital. National Organization for Rare Disorders (NORD). 2007; http://www.rarediseases.org/search/rdbdetail_abstract.html?disname=Afibrinogenemia%2C%20Congenital. Accessed 7/17/2009.
- Genetics Home Reference (GHR) contains information on Afibrinogenemia. This website is maintained by the National Library of Medicine.
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- The National Organization for Rare Disorders (NORD) is a federation of more than 130 nonprofit voluntary health organizations serving people with rare disorders. Click on the link to view information on this topic.
In Depth Information
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- The Online Mendelian Inheritance in Man (OMIM) database contains genetics resources that discuss Afibrinogenemia. Click on the link to go to OMIM and review these resources.
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