Your browser does not support javascript:   Search for gard hereSearch for news-and-events here.

Diseases

Genetic and Rare Diseases Information Center (GARD)

Print friendly version

Alström syndrome


Other Names for this Disease

  • ALMS
  • ALSS
  • Alstrom syndrome
  • Alstrom's syndrome
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Overview

Alström syndrome is a rare condition that affects many body systems.[1][2] The disorder is generally characterized by vision and hearing abnormalities, childhood obesity, diabetes mellitus, heart disease and slowly progressive kidney dysfunction which can lead to kidney failure.[2] Many of the signs and symptoms of this condition begin in infancy or early childhood, although some appear later in life. Alström syndrome is caused by mutations in the ALMS1 gene. It is inherited in an autosomal recessive pattern.[1] While there is no specific therapy for this condition, early diagnosis and intervention can moderate the progression and improve the longevity and quality of life for patients with the disease.[3]
Last updated: 12/8/2010

References

  1. Alström syndrome. Genetics Home Reference (GHR). 2008; http://ghr.nlm.nih.gov/condition/alstrom-syndrome. Accessed 12/8/2010.
  2. Alstrom Syndrome. National Organization for Rare Disorders (NORD). 2008; http://www.rarediseases.org/search/rdbdetail_abstract.html?disname=Alstrom+Syndrome. Accessed 12/8/2010.
  3. J.D. Marshall, S. Beck, P. Maffei, J.K. Naggert. Alström syndrome. Orphanet. 2007; http://www.orpha.net/consor/cgi-bin/OC_Exp.php?Lng=EN&Expert=64. Accessed 12/8/2010.
Your Questions Answered
by the Genetic and Rare Diseases Information Center

1 question(s) from the public on Alström syndrome have been answered. See questions and answers. You can also submit a new question.

Basic Information

  • Genetics Home Reference (GHR) contains information on Alström syndrome. This website is maintained by the National Library of Medicine.
  • MedlinePlus was designed by the National Library of Medicine to help you research your health questions, and it provides more information about this topic.
  • The National Organization for Rare Disorders (NORD) is a federation of more than 130 nonprofit voluntary health organizations serving people with rare disorders. Click on the link to view information on this topic.

In Depth Information

  • The Online Mendelian Inheritance in Man (OMIM) is a catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine. 
  • Orphanet is a European reference portal for information on rare diseases and orphan drugs.  Access to this database is free of charge.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Alström syndrome. Click on the link to view a sample search on this topic.

Insurance Issues

Other Names for this Disease
  • ALMS
  • ALSS
  • Alstrom syndrome
  • Alstrom's syndrome
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.