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Genetic and Rare Diseases Information Center (GARD)

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Antiphospholipid syndrome

Other Names for this Disease
  • Antiphospholipid antibody syndrome
  • APS
  • Familial antiphospholipid syndrome
  • Hughes syndrome
  • Lupus anticoagulant, familial
More Names
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Overview


Antiphospholipid syndrome is an autoimmune disorder. It is characterized by high levels of multiple different antibodies that are associated with clots in the arteries and veins. Symptoms vary and can include blood clots, miscarriage, rash, chronic headaches, dementia, and seizures. Treatment involves thinning the blood to reduce clotting.[1]

References

  1. NINDS Antiphospholipid Syndrome Information Page . National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/antiphosphlipid/antiphospholipid.htm. Accessed February 13, 2009.
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General Information

  • The Lupus Foundation of America has an information page on lupus and antiphospholipid antibodies. Click on Lupus Foundation of America to view the information page.
  • The March of Dimes has an information page on thrombophilia and pregnancy. Click on March of Dimes to view the information page.
  • The MayoClinic.com has a information page on antiphospholipid syndrome. Click on MayoClinic.com to view the information page.
  • Medscape Reference provides information on this topic. Click on the link to view this information. You may need to register to view the medical textbook, but registration is free.
  • MeSH® (Medical Subject Headings) is a terminology tool used by the National Library of Medicine. Click on the link to view information on this topic.
  • The National Human Genome Research Institute's (NHGRI) mission encompasses a broad range of studies aimed at understanding the structure and function of the human genome and its role in health and disease. Click on the link to view the information page on this topic.
  • The National Institute of Neurological Disorders and Stroke (NINDS) collects and disseminates research information related to neurological disorders. Click on the link to view information on this topic.
  • The National Organization for Rare Disorders (NORD) is a federation of more than 130 nonprofit voluntary health organizations serving people with rare disorders. Click on the link to view information on this topic.
  • Orphanet is a European reference portal for information on rare diseases and orphan drugs.  Access to this database is free of charge.  Click on the link to read information on this topic.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Antiphospholipid syndrome. Click on the link to view a sample search on this topic.
  • The The Online Mendelian Inheritance in Man (OMIM) database contains genetics resources that discuss Antiphospholipid syndrome. Click on the link to go to OMIM and review these resources.
  • UpToDate for patients has an information page on antiphospholipid syndrome. Click on UpToDate to view the information page.