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Diseases

Genetic and Rare Diseases Information Center (GARD)

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Aortic valve stenosis


Other Names for this Disease

  • Aortic stenosis
  • Valvular aortic stenosis
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Cause

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What causes aortic valve stenosis?

Aortic valve stenosis can be congenital (present at birth) or can develop later in life. When the condition is congenital, it is typically due to abnormal development of the aortic valve - either it forms abnormally narrow, or it is made up of one flap or leaflet (called a unicuspid valve, which is very rare) or two leaflets (bicuspid valve) instead of the usual three. Having a bicuspid valve can run in families. A bicuspid valve may not cause any problems until adulthood, when the valve begins to narrow or leak. In most cases, the exact underlying cause of congenital aortic valve stenosis is unknown.[6070] Aortic valve stenosis can also be caused by the buildup of calcium deposits on the heart valve with increasing age. This cause is most common in people older than 65. Rheumatic fever can also cause the condition because it may result in scar tissue forming on the valve, causing the leaflets to stiffen and fuse. Rheumatic fever can also cause a rough surface on the valve, which can lead to accumulation of calcium deposits later in life.[6070]
Last updated: 7/2/2013


Other Names for this Disease
  • Aortic stenosis
  • Valvular aortic stenosis
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.