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Diseases

Genetic and Rare Diseases Information Center (GARD)

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Becker muscular dystrophy


Other Names for this Disease

  • Becker's muscular dystrophy
  • Benign pseudohypertrophic muscular dystrophy
  • Muscular dystrophy pseudohypertrophic progressive, Becker type
  • Muscular dystrophy, Becker type
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Cause

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What causes Becker muscular dystrophy?

Becker muscular dystrophy (BMD) is caused by specific mutations in the DMD gene. The DMD gene gives instructions for making a protein called dystrophin. This protein helps stabilize and protect muscle fibers and may play a role in chemical signaling within cells. Mutations that lead to an abnormal "version" of dystrophin that keeps some of its function usually cause BMD. Muscle cells without fully functional dystrophin become damaged as muscles contract and relax with use. They then weaken and die over time, leading to the muscle weakness and heart problems in people with BMD.[1]
Last updated: 3/5/2014

References
  1. Duchenne and Becker muscular dystrophy. Genetics Home Reference (GHR). 2007; http://www.ghr.nlm.nih.gov/condition=duchenneandbeckermusculardystrophy. Accessed 11/18/2009.


Other Names for this Disease
  • Becker's muscular dystrophy
  • Benign pseudohypertrophic muscular dystrophy
  • Muscular dystrophy pseudohypertrophic progressive, Becker type
  • Muscular dystrophy, Becker type
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.