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Genetic and Rare Diseases Information Center (GARD)

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Bronchiolitis obliterans organizing pneumonia


Other Names for this Disease

  • BOOP
  • Constrictive bronchiolitis
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Overview

What is bronchiolitis obliterans organizing pneumonia (BOOP)?

What are the signs and symptoms of bronchiolitis obliterans organizing pneumonia (BOOP)?

What causes bronchiolitis obliterans organizing pneumonia (BOOP)?

How is bronchiolitis obliterans organizing pneumonia (BOOP) diagnosed?

How might bronchiolitis obliterans organizing pneumonia (BOOP) be treated?

What is bronchiolitis obliterans organizing pneumonia (BOOP)?

Bronchiolitis obliterans organizing pneumonia (BOOP) is a lung disease that causes inflammation in the small air tubes (bronchioles) and air sacs (alveoli). The signs and symptoms of BOOP often include shortness of breath, a dry cough, and fever. BOOP can be caused by viral infections, various drugs, and other medical conditions. If the cause is known, the condition is called secondary BOOP. In many cases, the underlying cause of BOOP is unknown. These cases are called idiopathic BOOP or cryptogenic organizing pneumonia. Treatment often includes corticosteroid medications.[1]
Last updated: 11/4/2011

What are the signs and symptoms of bronchiolitis obliterans organizing pneumonia (BOOP)?

The most common signs and symptoms of BOOP include shortness of breath (dyspnea), dry cough, and fever.[1] About half of affected individuals have a flu-like illness with cough, fever, fatigue, and weight loss.[2251]
Last updated: 9/13/2011

What causes bronchiolitis obliterans organizing pneumonia (BOOP)?

BOOP may be caused by a variety of factors, including viral infections, inhalation of toxic gases, drugs, connective tissue disorders, radiation therapy, cocaine, inflammatory bowl disease, and HIV infection. In many cases, the underlying cause of BOOP is unknown. These cases are called idiopathic BOOP or cryptogenic organizing pneumonia (COP).[1]
Last updated: 9/20/2010

How is bronchiolitis obliterans organizing pneumonia (BOOP) diagnosed?

BOOP is typically diagnosed by lung biopsy, although imaging tests and pulmonary function tests can also provide information for diagnosis.[2]
Last updated: 9/20/2010

How might bronchiolitis obliterans organizing pneumonia (BOOP) be treated?

Most cases of BOOP respond well to treatment with corticosteroids. If the condition is caused by a particular drug, stopping the drug can also improve a patient's condition.[1]
Last updated: 9/20/2010

References
  1. Vasu TS, Cavallazzi R, Hirani A, Sharma D, Weibel SB, Kane GC. Respitatory Care. August 2009; 54(8):1028-32. http://www.rcjournal.com/contents/08.09/08.09.1028.pdf. Accessed 9/13/2011.
  2. King TE. Idiopathic Interstitial Pneumonias. Merck Manual for Healthcare Professionals. May 2008; http://www.merckmanuals.com/professional/pulmonary_disorders/interstitial_lung_diseases/idiopathic_interstitial_pneumonias.html?qt=Bronchiolitis%20obliterans%20organizing%20pneumonia%20&alt=sh. Accessed 9/13/2011.


Other Names for this Disease
  • BOOP
  • Constrictive bronchiolitis
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.