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Other Names for this Disease
- Hepatic vein obstruction
- Hepatic veno-occlusive disease
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 This narrowing or obstruction slows or prevents blood from flowing out of the liver and back to the heart which can lead to liver damage. While some people experience no symptoms, many experience fatigue, abdominal pain, nausea, and jaundice. Other associated findings include an accumulation of fluid in the abdomen (ascites), an enlarged spleen and/or liver, and severe bleeding in the esophagus. The severity of the disorder varies from case to case, depending on the site and number of affected veins. Drugs may be used to dissolve or decrease the size of the obstruction (if it is a clot). In some cases surgery is performed. In most cases, the cause of Budd-Chiari syndrome is unknown.Budd-Chiari syndrome is a rare disorder characterized by narrowing and obstruction of the veins of the liver.
Last updated: 10/30/2010
- Budd Chiari Syndrome. National Organization for Rare Disorders (NORD). 2007; http://www.rarediseases.org/search/rdbdetail_abstract.html?disname=Budd%20Chiari%20Syndrome. Accessed 10/30/2010.
- Dugdale DC, Longstreth GF. Hepatic vein obstruction (Budd-Chiari). MedlinePlus. 2010; http://www.nlm.nih.gov/medlineplus/ency/article/000239.htm. Accessed 10/30/2010.
- Shaffer EA. Budd-Chiari Syndrome. Merck Online Medical Library . 2007; http://www.merck.com/mmhe/sec10/ch138/ch138d.html. Accessed 10/30/2010.
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In Depth Information
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- The Online Mendelian Inheritance in Man (OMIM) database contains genetics resources that discuss Budd-Chiari syndrome. Click on the link to go to OMIM and review these resources.
- Orphanet is a European reference portal for information on rare diseases and orphan drugs. Access to this database is free of charge.
- PubMed is a searchable database of medical literature and lists journal articles that discuss Budd-Chiari syndrome. Click on the link to view a sample search on this topic.