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Burkitt lymphoma
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Overview
Burkitt lymphoma (BL) is a rare, aggressive form of B-cell non-Hodgkin's lymphoma, a type of cancer that affects the organs of the immune system. It is more common in males than females. Three forms exist: one endemic to Africa that is linked to the Epstein Barr virus (EBV); a sporadic form that develops mainly in the abdomen; and an immunodeficiency-associated form that occurs most commonly in individuals with HIV infection.[1][2] BL can also develop in the ear, nose, throat and more rarely in other locations.[1] Signs and symptoms may differ depending on the form of BL and the organs or body systems affected.[2] The exact cause of the condition is not known. Treatment typically includes a few months of intensive chemotherapy; the current cure rate is estimated to be about 80-90%.[1]
References
- Catherine Patte. Burkitt lymphoma. Orphanet. http://www.orpha.net/consor/cgi-bin/OC_Exp.php?Expert=543&lng=EN. Accessed 6/26/2012.
- Ali H Kanbar. Burkitt Lymphoma and Burkitt-like Lymphoma. Medscape Reference. http://emedicine.medscape.com/article/1447602-overview. Accessed June 26, 2012.
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General Information
- MedlinePlus, a Web site designed by the National Library of Medicine to help you research your health questions, provides more information about this topic. Click on the link to view this information.
- Medscape Reference provides information on this topic. Click on the link to view this information. You may need to register to view the medical textbook, but registration is free.
- The Merck Manuals Online Medical Library provides information on this condition. Click on the link to view the information.
- The National Cancer Institute provides the most current information on cancer for patients, health professionals, and the general public. Click on the link to view information on this topic.
- Orphanet is a European reference portal for information on rare diseases and orphan drugs. Access to this database is free of charge. Click on the link to read information on this topic.
- PubMed is a searchable database of medical literature and lists journal articles that discuss Burkitt lymphoma. Click on the link to view a sample search on this topic.
- The The Online Mendelian Inheritance in Man (OMIM) database contains genetics resources that discuss Burkitt lymphoma. Click on the link to go to OMIM and review these resources.
