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Genetic and Rare Diseases Information Center (GARD)

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Cerebellar degeneration


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Overview

Cerebellar degeneration refers to the deterioration of neurons in the cerebellum (the area of the brain that controls muscle coordination and balance). Conditions that cause cerebellar degeneration may also affect other areas of the central nervous system, such as the spinal cord, the cerebral cortex, and the brain stem. Signs and symptoms of cerebellar degeneration may include a wide-based, uncoordinated walk; a back and forth tremor in the trunk of the body; uncoordinated movements of the arms and legs; slow and slurred speech; and nystagmus. Cerebellar degeneration can be caused by a variety of factors including inherited gene changes (mutations), chronic alcohol abuse, and paraneoplastic disorders. Treatment for cerebellar degeneration varies depending on the underlying cause.[1]
Last updated: 12/14/2014

References

  1. NINDS Cerebellar Degeneration Information Page. National Institute of Neurological Disorders and Stroke. February 2014; http://www.ninds.nih.gov/disorders/cerebellar_degeneration/cerebellar_degeneration.htm.
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Basic Information

In Depth Information

  • The Merck Manual for health care professionals provides information on Cerebellar degeneration.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Cerebellar degeneration. Click on the link to view a sample search on this topic.
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.