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Diseases

Genetic and Rare Diseases Information Center (GARD)

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Cerebellar degeneration


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Treatment

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How might cerebellar degeneration be treated?

There is currently no cure for hereditary forms of cerebellar degeneration. In these cases, treatment is usually supportive and based on the signs and symptoms present in each person. For example, a variety of drugs may be used to treat gait abnormalities. Physical therapy can strengthen muscles, while special devices or appliances can assist in walking and other activities of daily life.[1]

In acquired (non-genetic and non-inherited) forms of cerebellar degeneration, some signs and symptoms may be reversible with treatment of the underlying cause.[2] For example, paraneoplastic cerebellar degeneration may improve after successful treatment of the underlying cancer. For alcoholic/nutritional cerebellar degeneration, symptoms are often relieved with discontinuation of alcohol abuse, a normal diet and dietary supplementation with thiamine and other B vitamins.[3]
Last updated: 12/15/2014

References
  1. NINDS Ataxias and Cerebellar or Spinocerebellar Degeneration Information Page. National Institute of Neurological Disorders and Stroke. April 2014; http://www.ninds.nih.gov/disorders/ataxia/ataxia.htm.
  2. Cerebellar Disorders. Merck Manual. August 2013; http://www.merckmanuals.com/professional/neurologic_disorders/movement_and_cerebellar_disorders/cerebellar_disorders.html?qt=&sc=&alt=.
  3. Cerebellar Degeneration, Subacute. NORD. 2007; http://www.rarediseases.org/search/rdbdetail_abstract.html?disname=Cerebellar%20Degeneration%2C%20Subacute.


Clinical Trials & Research for this Disease

  • ClinicalTrials.gov lists trials that are studying or have studied Cerebellar degeneration. Click on the link to go to ClinicalTrials.gov to read descriptions of these studies.
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.