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Diseases

Genetic and Rare Diseases Information Center (GARD)

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Chandler's syndrome


Other Names for this Disease

  • Chandler syndrome
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Overview

Chandler's syndrome is a rare eye disorder in which the single layer of cells lining the interior of the cornea proliferates, causing changes within the iris, corneal swelling, and unusually high pressure in the eye (glaucoma). This condition is one of three syndromes, along with progressive iris atrophy and Cogan-Reese syndrome, that make up the iridocorneal endothelial (ICE) syndrome. In most cases, only one eye is affected.[1][2] Symptoms may include reduced vision and pain.[1][2] Chandler's syndrome more often affects females and usually presents sometime during middle age.[1] The cause of this disease is unknown.[2]
Last updated: 8/11/2014

References

  1. Shields B, Sears ML. Chandler's Syndrome. National Organization for Rare Disorders (NORD). 2013; http://www.rarediseases.org/rare-disease-information/rare-diseases/byID/949/viewAbstract. Accessed 8/11/2014.
  2. Facts About The Cornea and Corneal Disease. National Eye Institute (NEI). May 2013; http://www.nei.nih.gov/health/cornealdisease/#g. Accessed 8/11/2014.
Your Questions Answered
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Basic Information

  • The National Eye Institute (NEI) was established by Congress in 1968 to protect and prolong the vision of the American people. Click on the link to view information on this topic. 
  • The National Organization for Rare Disorders (NORD) is a federation of more than 130 nonprofit voluntary health organizations serving people with rare disorders. Click on the link to view information on this topic.

In Depth Information

  • PubMed is a searchable database of medical literature and lists journal articles that discuss Chandler's syndrome. Click on the link to view a sample search on this topic.
Other Names for this Disease
  • Chandler syndrome
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.