Chronic granulomatous disease
Other Names for this Disease
- Granulomatous disease, chronic
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primary immune deficiency disorder that affects certain white blood cells. It is characterized by an inability to resist repeated infectious diseases and a tendency to develop chronic inflammation. Symptoms usually begin in infancy or childhood and include life-threatening recurrent fungal and bacterial infections affecting the skin, lungs, and bones; swollen areas of inflamed tissues known as granulomas; and other symptoms. It is caused by mutations in any one of four different genes and is usually inherited in an autosomal recessive or X-linked recessive manner. Treatment consists of continuous antibiotic therapy to help prevent infections and corticosteroid drugs for treating granulomatous complications.Chronic granulomatous disease (CGD) is a rare, inherited,
Last updated: 5/12/2011
- Granulomatous Disease, Chronic. NORD. January 14, 2009; http://www.rarediseases.org/search/rdbdetail_abstract.html?disname=Granulomatous%20Disease%2C%20Chronic. Accessed 5/12/2011.
- The American Society of Gene & Cell Therapy provides information on the treatment of immunodeficiency diseases.
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- Online Mendelian Inheritance in Man (OMIM) is a catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine.
CGD, autosomal recessive, cytochrome b-positive, type I
CGD, autosomal recessive, cytochrome b-positive, type II
CGD, autosomal recessive, cytochrome b-negative
CGD, autosomal dominant type
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