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Diseases

Genetic and Rare Diseases Information Center (GARD)

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Coats disease


Other Names for this Disease
  • Retinal telangiectasis
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Treatment


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How might Coats disease be treated?

The treatment of Coats disease depends on the signs and symptoms present in each individual and the stage at which the individual is diagnosed.[1] Treatment is usually directed towards closing the vessels that are leaking and salvaging as much vision as possible.[2] A procedure that uses extreme cold to destroy the blood vessels (cryotherapy), and/or a procedure that uses intense, focused light (laser therapy) to heat and destroy tissue may be used alone or in combination to treat the telangiectasia associated with the disease.[1] These procedures are commonly used during the early stages of the disease.[2] More advanced cases may require surgical treatment.[2]. Surgery to reattach the retina may be necessary for retinal detachment.[1] Drainage of fluid or surgically removing the substances that fill the eyeball between the lens and the retina (vitrectomy) may also be used to treat Coats disease when a retinal detachment is present. A procedure in which the vessels involved are heated and destroyed (diathermy) has also been used to treat the disease.[1]
Last updated: 12/5/2011

References
  1. Coats disease. NORD. April 21, 2008; http://www.rarediseases.org/rare-disease-information/rare-diseases/byID/837/viewAbstract. Accessed 12/2/2011.
  2. A. Del Longo. Coats disease. Orphanet. September 2004; http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=EN&Expert=190. Accessed 12/2/2011.


Management Guidelines

  • GeneReviews provides current, expert-authored, peer-reviewed, full-text articles describing the application of genetic testing to the diagnosis, management, and genetic counseling of patients with specific inherited conditions. Click on the link to view the article on this topic.

Clinical Trials & Research for this Disease

  • ClinicalTrials.gov lists trials that are studying or have studied Coats disease. Click on the link to go to ClinicalTrials.gov to read descriptions of these studies.
  • Orphanet lists clinical trials, research studies, and patient registries enrolling people with this condition. Click on Orphanet to view the list.