- Cockayne's syndrome
- Dwarfism-retinal atrophy-deafness syndrome
- Progeria-like syndrome
- Progeroid nanism
Your QuestionI have a friend whose toddler son was diagnosed with Cockayne syndrome. I would really like some more information about this condition and the survival rate for his son.
We have identified the following information that we hope you find helpful. If you still have questions, please contact us.
The prognosis for Cockayne syndrome varies by the disease type. There are three types of Cockayne syndrome:
Cockayne Syndrome Type 1 (type A) is marked by normal development until a child is 1 or 2 years old, at which point growth slows and developmental delays are noticed. Life expectancy for type 1 is approximately 10 to 20 years.Cockayne syndrome type 2 (type B), also known as cerebro-oculo-facio-skeletal (COFS) and Pena-Shokeir syndrome type II, has severe symptoms present at birth and normal brain development stops after birth. Average lifespan for children with type 2 is up to 7 years of age.
Cockayne syndrome type 3 (type C) appears later in childhood with milder symptoms than the other types and a slower progression of the disorder. Individuals with this type of Cockayne syndrome live into adulthood, with an average lifespan of 40 to 50 years.
- Cockayne Syndrome Brochure. Share & Care Cockayne Syndrome Network. 2008; http://cockaynesyndrome.net/main/AboutCS.aspx. Accessed 5/27/2011.
- Genetics Home Reference. Cockayne Syndrome. May 2010; http://ghr.nlm.nih.gov/condition/cockayne-syndrome. Accessed 5/27/2011.
- Edward G. Neilan, PhD. Cockayne Syndrome. Gene Reviews. 2006; http://www.ncbi.nlm.nih.gov/books/NBK1342/. Accessed 5/27/2011.