Cold agglutinin disease
Other Names for this Disease
- Anemia, hemolytic, cold antibody
- Chronic cold agglutinin disease
- Cold agglutinin syndrome
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Cold agglutinin disease (CAD) is not an inherited condition and does not run in families. It is designated as either idiopathic or primary (not associated with an underlying condition), or secondary (associated with or caused by another condition). In some cases CAD may be multifactorial, which means that multiple environmental factors and multiple genes may interact to predispose a person to developing CAD. However, to our knowledge, no disease-causing genes have been identified and no familial cases have been reported.
Last updated: 5/15/2014
- Marc Michel. Cold agglutinin disease. Orphanet. August, 2010; http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=EN&Expert=56425. Accessed 5/15/2014.