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Diseases

Genetic and Rare Diseases Information Center (GARD)

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Conjunctivitis ligneous


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Overview


Ligneous conjunctivitis is a rare disorder characterized by the buildup of a protein called fibrin which causes inflammation of the conjunctiva (conjunctivitis) and leads to thick, woody (ligneous), inflamed growths that are yellow, white, or red. Ligneous conjunctivitis most often occurs on the inside of the eyelids, but may also affect the sclera, cornea and pupil, leading to vision loss.[1] A systemic form of the condition may occur, affecting the mucous membranes of the larynx, vocal chords, nose, trachea, bronchi, vagina, cervix, and gingiva. The cause of ligneous conjunctivitis is unknown. Autosomal recessive inheritance has been suggested in some cases.[2] Ligneous conjunctivitis is sometimes associated with a condition known as congenital plasminogen deficiency.
Last updated: 4/29/2013

References

  1. Congenital plasminogen deficiency. Genetics Home Reference (GHR). August 2012; http://ghr.nlm.nih.gov/condition/congenital-plasminogen-deficiency. Accessed 4/29/2013.
  2. Conjunctivitis, Ligneous. National Organiation for Rare Disorders (NORD). 2007; http://www.rarediseases.org/rare-disease-information/rare-diseases/byID/863/viewAbstract. Accessed 4/29/2013.
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