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Diseases

Genetic and Rare Diseases Information Center (GARD)

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Cowden syndrome


Other Names for this Disease
  • CD
  • Cowden disease
  • Cowden's disease
  • CS
  • MHAM
More Names
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Inheritance


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How is Cowden syndrome inherited?

Cowden syndrome is inherited in an autosomal dominant pattern, which means one copy of the altered gene in each cell is sufficient to increase the risk of developing noncancerous and cancerous tumors.  In some cases, an affected person inherits the mutation from one affected parent. Other cases may result from new mutations in the gene. These cases occur in people with no history of the disorder in their family. A person with Cowden syndrome has a 50% chance with each pregnancy of passing along the altered gene to his or her child. [1]
Last updated: 10/23/2012

References
  1. Cowden syndrome. Genetics Home Reference (GHR). March 2006; http://ghr.nlm.nih.gov/condition=cowdensyndrome. Accessed 5/18/2011.