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Genetic and Rare Diseases Information Center (GARD)

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Cri du chat syndrome


Other Names for this Disease
  • 5p deletion syndrome
  • 5p minus syndrome
  • 5p- syndrome
  • Cat cry syndrome
  • Chromosome 5p deletion syndrome
More Names
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Your Question

Is yelling and aggression a common behavioral characteristic of cri du chat syndrome?

Our Answer

We have identified the following information that we hope you find helpful. If you still have questions, please contact us.

Is aggression common in adults with cri du chat syndrome?

Several research studies have been completed to look at the prevalence of aggressive behavior in children and adults with cri du chat syndrome (CCS). Studies completed in this area have shown that many individuals with CCS have aggressive behaviors toward others that last into adulthood. One study demonstrated that 70.2% of individuals with CCS studied displayed some amount of behavioral aggression. Within this study, it was found that individuals aged over 21 tended to have less physical aggression, such as biting or hitting (15.0%), and more non-physical aggression, such as yelling (64.7%).[1]

Another study completed in 2002 found that of their 66 participants, only 8 (12%) displayed no aggressive behavior, while 8 participants displayed only one type of aggressive behavior and the remaining 50 displayed two or more aggressive behaviors. These include physical aggressive behaviors, such as hitting others with own body parts (65.2%),  hitting others with objects (36.4%), and meanness or cruelty to others (39.4%). 23.1% of individuals displayed meanness on a weekly basis while 26.9% displayed meanness on a daily basis.[2] A third research study found that out of ten participants with CCS, 4 displayed a large range of aggression and disruptive behavior.[3]

Last updated: 7/3/2013

References
  • Arron K, Oliver C, Moss J, Berg K, Burbidge C . The prevalence and phenomenology of self-injurious and aggressive behavior in genetic syndromes. Journal of Intellectual Disability Research. 2011;55(2):109-120; http://www.ncbi.nlm.nih.gov/pubmed/20977515. Accessed 6/21/2013.
  • Collins MSR, Cornish K. A survey of the prevalence of stereotypy, self-injury and aggression in children and young adults with Cri du Chat syndrome. Journal of Intellectual Disability Research. 2002; 46(2):133-140; http://www.ncbi.nlm.nih.gov/pubmed/11869383. Accessed 6/21/2013.
  • Teixeira M et al., . A description of adaptive and maladaptive behavior in children and adolescents with Cri-du-chat syndrome. J Intellect Disabil Res. 2011 Feb;55(2):132-7; http://www.ncbi.nlm.nih.gov/pubmed/21205041. Accessed 6/21/2013.