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Genetic and Rare Diseases Information Center (GARD)

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Cushing's syndrome


Other Names for this Disease

  • Adrenal cortex adenoma
  • Adrenal hyperfunction resulting from pituitary acth excess
  • Cushing syndrome
  • Ectopic ACTH syndrome
  • Ectopic adrenocorticotropic hormone syndrome
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Overview

Cushing's syndrome is an endocrine disorder caused by prolonged exposure of the body's tissues to high levels of cortisol, a hormone produced by the adrenal gland. Excess cortisol may be the result of long-term use of corticosteroid medications or tumors in the pituitary or adrenal glands. Symptoms of Cushing's syndrome include obesity, fatigue, muscle weakness, high blood pressure, high blood sugar, easy bruising and stretch marks. Treatment depends on the underlying cause, but may include decreasing the dosage of corticosteroids or removing the causative tumor.[1][2]
Last updated: 2/26/2013

References

  1. NINDS Cushing's Syndrome Information Page. National Institute of Neurological Disorders and Stroke (NINDS). October 26, 2010; http://www.ninds.nih.gov/disorders/cushings/cushings.htm. Accessed 2/26/2013.
  2. Cushing's Syndrome. National Endocrine and Metabolic. April 2012; http://www.endocrine.niddk.nih.gov/pubs/cushings/cushings.aspx. Accessed 2/26/2013.
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Basic Information

In Depth Information

  • Online Mendelian Inheritance in Man (OMIM) is a catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine. 
  • Orphanet is a European reference portal for information on rare diseases and orphan drugs.  Access to this database is free of charge.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Cushing's syndrome. Click on the link to view a sample search on this topic.
Other Names for this Disease
  • Adrenal cortex adenoma
  • Adrenal hyperfunction resulting from pituitary acth excess
  • Cushing syndrome
  • Ectopic ACTH syndrome
  • Ectopic adrenocorticotropic hormone syndrome
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.