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Genetic and Rare Diseases Information Center (GARD)

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Cushing's syndrome

Other Names for this Disease
  • Adrenal cortex adenoma
  • Adrenal hyperfunction resulting from pituitary acth excess
  • Cushing syndrome
  • Ectopic ACTH syndrome
  • Ectopic adrenocorticotropic hormone syndrome
More Names
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What are the signs and symptoms of Cushing's syndrome?

The symptoms of Cushing's syndrome may include upper body obesity, severe fatigue and muscle weakness, high blood pressure, backache, elevated blood sugar, easy bruising, and bluish-red stretch marks on the skin of the abdomen, thighs, buttocks, arms and breasts. Women with Cushing's syndrome may experience an increase in growth of facial and body hair, and menstrual periods may become irregular or cease.[1][2] Men may have decreased fertility, diminished sexual desire, and/or erectile dysfunction.[2] Neurological symptoms may include difficulties with memory and neuromuscular disorders.[1]
Last updated: 2/26/2013

  1. NINDS Cushing's Syndrome Information Page. National Institute of Neurological Disorders and Stroke (NINDS). October 26, 2010; Accessed 2/26/2013.
  2. Cushing's Syndrome. National Endocrine and Metabolic. April 2012; Accessed 2/26/2013.