Other Names for this Disease
- Adrenal cortex adenoma
- Adrenal hyperfunction resulting from pituitary acth excess
- Cushing syndrome
- Ectopic ACTH syndrome
- Ectopic adrenocorticotropic hormone syndrome
The signs and symptoms of Cushing's syndrome may include:
- Upper body obesity
- Severe fatigue
- Muscle weakness
- High blood pressure
- Elevated blood sugar
- Easy bruising
- Bluish-red stretch marks on the skin
- Neurological issues
Women with Cushing's syndrome may also experience increased growth of facial and body hair, and menstrual periods may become irregular or cease. Men may have decreased fertility, diminished sexual desire, and/or erectile dysfunction.
The Human Phenotype Ontology provides the following list of signs and symptoms for Cushing's syndrome. If the information is available, the table below includes how often the symptom is seen in people with this condition. You can use the MedlinePlus Medical Dictionary to look up the definitions for these medical terms.
The Human Phenotype Ontology (HPO) has collected information on how often a sign or symptom occurs in a condition. Much of this information comes from Orphanet, a European rare disease database. The frequency of a sign or symptom is usually listed as a rough estimate of the percentage of patients who have that feature.
The frequency may also be listed as a fraction. The first number of the fraction is how many people had the symptom, and the second number is the total number of people who were examined in one study. For example, a frequency of 25/25 means that in a study of 25 people all patients were found to have that symptom. Because these frequencies are based on a specific study, the fractions may be different if another group of patients are examined.
Sometimes, no information on frequency is available. In these cases, the sign or symptom may be rare or common.
- NINDS Cushing's Syndrome Information Page. National Institute of Neurological Disorders and Stroke. July 2013; http://www.ninds.nih.gov/disorders/cushings/cushings.htm.
- Cushing's Syndrome. National Endocrine and Metabolic. April 2012; http://www.endocrine.niddk.nih.gov/pubs/cushings/cushings.aspx. Accessed 2/26/2013.