Other Names for this Disease
- Darier White Disease
- Darier's disease
- Darier-White disease
- Keratosis follicularis
mutations in the ATP2A2 gene and inherited in an autosomal dominant fashion.Darier disease is an inherited skin condition characterized by wart-like blemishes on the body usually located on the scalp, forehead, upper arms, chest, back, knees, elbows, and behind the ear. Other features of Darier disease include nail abnormalities, such as red and white streaks in the nails with an irregular texture, and small pits in the palms of the hands and soles of the feet. The severity of the disease varies over time. A form of Darier disease known as the linear or segmental form is characterized by blemishes on localized areas of the skin. Darier disease is not an infection and the blemishes are not contagious. Symptoms usually first appear in late childhood or early adulthood. This condition is caused by
Last updated: 3/6/2014
- Darier disease. Genetics Home Reference. March 2008; http://ghr.nlm.nih.gov/condition=darierdisease. Accessed 3/6/2014.
- Genetics Home Reference (GHR) contains information on the P2RY12 gene and its related conditions. This website is maintained by the National Library of Medicine.
- DermNetNZ provides information on ichthyosis in general. DermNetNZ is an online resource about skin diseases developed by the New Zealand Dermatological Society Incorporated.
- The National Organization for Rare Disorders (NORD) is a federation of more than 130 nonprofit voluntary health organizations serving people with rare disorders. Click on the link to view information on this topic.
- Medscape Reference provides information on this topic. Click on the link to view this information. You may need to register to view the medical textbook, but registration is free.
- Online Mendelian Inheritance in Man (OMIM) is a catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine.
- Orphanet is a European reference portal for information on rare diseases and orphan drugs. Access to this database is free of charge.
- PubMed is a searchable database of medical literature and lists journal articles that discuss Darier disease. Click on the link to view a sample search on this topic.
- You can read more about Darier disease and see images of the skin lesions on DermNet, the website of the New Zealand Dermatological Society Incorporated. DermNet provides facts about the skin for consumers and health professionals.