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Diseases

Genetic and Rare Diseases Information Center (GARD)

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Devic disease


Other Names for this Disease

  • Devic syndrome
  • Devic's neuromyelitis optica
  • Neuromyelitis optica
  • NMO
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Overview

Devic disease, is an autoimmune condition that affects the spinal cord and optic nerves (the nerves that carry information regarding sight from the eye). In Devic disease, the body's immune system attacks and destroys myelin, a fatty substance that surrounds nerves and helps nerve signals move from cell to cell.[1] Signs and symptoms worsen with time and include optic neuritistransverse myelitis; pain in spine and limbs; and bladder and bowel dysfunction. The exact cause of Devic disease is unknown. Most affected people do not have other family members with the condition.[2] Currently there is no cure for Devic disease, but there are therapies to treat an attack while it is happening, to reduce symptoms, and to prevent relapses.[1]
Last updated: 12/5/2014

References

  1. NINDS Neuromyelitis Optica Information Page. National Institute of Neurological Disorders and Stroke (NINDS). 2007; http://www.ninds.nih.gov/disorders/neuromyelitis_optica/neuromyelitis_optica.htm. Accessed 11/18/2009.
  2. Neuromyelitis Optica. NORD. March 2012; http://rarediseases.org/rare-disease-information/rare-diseases/byID/479/viewFullReport.
Your Questions Answered
by the Genetic and Rare Diseases Information Center

3 question(s) from the public on Devic disease have been answered. See questions and answers. You can also submit a new question.

Basic Information

In Depth Information

  • The Merck Manual for health care professionals provides information on Devic disease.
  • Orphanet is a European reference portal for information on rare diseases and orphan drugs.  Access to this database is free of charge.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Devic disease. Click on the link to view a sample search on this topic.

Selected Full-Text Journal Articles

Other Names for this Disease
  • Devic syndrome
  • Devic's neuromyelitis optica
  • Neuromyelitis optica
  • NMO
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.