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Dubin-Johnson syndrome

Other Names for this Disease
  • Chronic Idiopathic Jaundice
  • Conjugated Hyperbilirubinemia
  • DJS
  • Hyperbilirubinemia 2
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Dubin-Johnson syndrome is a type of hereditary hyperbilirubinemia with a relatively benign course.[1] Symptoms may include a yellowish color to the skin (jaundice), and a liver that is sometimes enlarged and tender.[2]  The symptoms often do not present until puberty or adulthood. The syndrome interferes with the body's ability to move bilirubin from the liver. In most cases, treatment is not required.[3] 
Last updated: 12/19/2008


  1. Habashi SL, Lambiase LR, MK Anand, KJ Mishark, Nguyen C . Dubin-Johnson Syndrome. eMedicine. October 10, 2006; Accessed 12/19/2008.
  2. Dubin Johnson Syndrome. National Organization for Rare Disorders (NORD). 2007; Accessed 12/19/2008.
  3. Dugdale, DC. Dubin-Johnson syndrome. MedlinePlus. July 22, 2008; Accessed 12/19/2008.
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Basic Information

  • Genetics Home Reference (GHR) contains information on Dubin-Johnson syndrome. This website is maintained by the National Library of Medicine.
  • MedlinePlus was designed by the National Library of Medicine to help you research your health questions, and it provides more information about this topic.
  • The National Organization for Rare Disorders (NORD) is a federation of more than 130 nonprofit voluntary health organizations serving people with rare disorders. Click on the link to view information on this topic.

In Depth Information

  • Medscape Reference provides information on this topic. Click on the link to view this information. You may need to register to view the medical textbook, but registration is free.
  • The Online Mendelian Inheritance in Man (OMIM) is an catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine. 
  • Orphanet is a European reference portal for information on rare diseases and orphan drugs.  Access to this database is free of charge.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Dubin-Johnson syndrome. Click on the link to view a sample search on this topic.